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August 09, 2008

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Dr Terence Koh

Your vivid description of the excitement at ICAD 2008 was interesting.

However, I think the interest was not really on flurizan but on the new discovery by Taurx therapeutics and their drug rember that slowed the deterioration of Alzheimer's disease by 81%. That was ground breaking news.

Mona Johnson

Dr. Koh has anticipated my next post, which will be about the Phase 2 results for Rember. I wrote about Flurizan first because, like Rember, it showed promise in Phase 2 trials.

But I wish we could wait for the results of the Phase 3 trials of Rember before the hype begins. I think it's cruel to raise the hopes of people with memory loss and their families about potential treatments until there is solid evidence that they work.

Don Moyer

Yes, yes, Mona! The Rember hype generated lots of excitement in the emails among our fellow travelers far out of proportion to the limitations of phase 2 trials. I'm so sorry that the hypers have such limited understanding of the cruelity they're responsible for. Don

Gail Rae Hudson

All three comments echo EXACTLY what I was thinking as I read this post, "What about Rember?" Remember the article I wrote you about, Mona, while you were at ICAD? It was, specifically, the hype that was exciting, not the report of the Phase 2 results, which were, frankly, ho hum.
I know everyone wants a cure, or at least a good way of managing dementia, Alzheimer's included. I wonder, though, if part of the problem is that we, as a species, haven't actually lived with dementia as a common element within a demographic to understand how to manage it, let alone cure it. It is a triumph for us that, in many nations, many members of our species are living as long as they are. Now, it seems, we need to settle down post-Triumph-One and figure out what old age is, what we want it to be and how to bridge the gap. Although my sociology may be faulty, it seems to be that we've had to do this with all other demographics. So, the core problem isn't a new one, and, as well, we have experience coming up with solutions (and changing the solutions). I wonder...maybe when we, as a species, reach "Phase 2" in our understanding of old age, that is when our adaptations for the current problems of old age will begin to have the flavor of real solutions.
Did I say that right? I'm not sure.

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