Looking back through Dad’s medical records, I found the results of some genetic tests. Did his genes explain what happened to him? Were his dementia and death already set in stone the day he was born? Or maybe by the time this picture was taken?
I remember that one of his neurologists had said that my father didn’t have the gene that may increase the risk of developing Alzheimer’s. To see if I could get a better understanding, I thumbed through Dad’s records looking at all the pages with the words “gene” or “genotype”.
Here’s what I found:
Apolipoprotein E Genotype: 2 and 3
Methylenetetrahydrofolate reductase (MHTFR) FRET genotype analysis to identify the C677T polymorphism. Genotype result: A/A
Analysis for C282Y mutation, H63D mutation and S65C mutation…
The Apoliprotein E Gene is the one the neurologist told me is associated with Alzheimer’s Disease. The C282Y, H63D and S65C mutations are associated with iron overload, which this same neurologist suspected might be a problem. But I have no idea with the C677T polymorphism is, or what all of this means. I’ll try to find some answers, and will post any results.